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    gpa33a glycoprotein A33 (transmembrane), paralog a [ Danio rerio (zebrafish) ]

    Gene ID: 407680, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gpa33aprovided by ZNC
    Official Full Name
    glycoprotein A33 (transmembrane), paralog aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080229-4
    See related
    Ensembl:ENSDARG00000100223 AllianceGenome:ZFIN:ZDB-GENE-080229-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sc:d0144; si:zfos-1011f11.1
    Summary
    Predicted to act upstream of or within cell morphogenesis and immune response. Predicted to be located in plasma membrane. Is expressed in several structures, including EVL; digestive system; epidermis; periderm; and sensory system. Orthologous to human GPA33 (glycoprotein A33). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See gpa33a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (65705..71523, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (65705..71666, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin-like domain-containing receptor 2 Neighboring gene immunoglobulin-like domain containing receptor 1a Neighboring gene coagulation factor VII, like Neighboring gene coagulation factor VII

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary context can clarify gene names: Teleosts as a case study. Gasanov EV, et al. Bioessays, 2021 Jun. PMID 33829511
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glycoprotein A33 (transmembrane), paralog a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115105.2 → NP_001108577.2  glycoprotein A33 (transmembrane), paralog a precursor

      Status: VALIDATED

      Source sequence(s)
      BC067681, FP475876
      UniProtKB/TrEMBL
      A0A0R4IIH3, A0A8M1NG43, Q6NW88
      Related
      ENSDARP00000135435.2, ENSDART00000165650.2
      Conserved Domains (3) summary
      smart00408
      Location:161 → 224
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:30 → 142
      IG_like; Immunoglobulin like
      cl11960
      Location:35 → 143
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      65705..71523 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353526.3 → XP_017209015.2  glycoprotein A33 (transmembrane), paralog a isoform X1

      UniProtKB/TrEMBL
      Q6NW88
      Related
      ENSDARP00000138102.1, ENSDART00000165267.1

    2. XM_068217059.1 → XP_068073160.1  glycoprotein A33 (transmembrane), paralog a isoform X2

      UniProtKB/TrEMBL
      Q6NW88

    3. XM_068217070.1 → XP_068073171.1  glycoprotein A33 (transmembrane), paralog a isoform X3

      UniProtKB/TrEMBL
      A0A8M9P6M7, Q6NW88

    4. XM_068217051.1 → XP_068073152.1  glycoprotein A33 (transmembrane), paralog a isoform X2

      UniProtKB/TrEMBL
      Q6NW88
    Nucleotide Protein Strain
    Heading Accession and Version

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