eif5a2 eukaryotic translation initiation factor 5A2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eif5a2provided by ZNC
Official Full Name: eukaryotic translation initiation factor 5A2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2405
See related: Ensembl:ENSDARG00000056186 AllianceGenome:ZFIN:ZDB-GENE-040426-2405
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: EIF5A; zgc:55504; zgc:77429; wu:fb05b06; wu:fc23f04; wu:fc61c10
Summary: Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translational initiation. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human EIF5A2 (eukaryotic translation initiation factor 5A2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (25839272..25845027)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (26183638..26189393)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc61c10 (e-PCR)
- UniSTS:189470

fc23f04.x1 (e-PCR)
- UniSTS:193156

fb05b06.x1 (e-PCR)
- UniSTS:189884

fb05b06.x1 (e-PCR)
- UniSTS:189885

fc23f04.x1 (e-PCR)
- UniSTS:187838

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables ribosome binding	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of translational elongation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of translational elongation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of translational termination	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of translational termination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translational elongation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 5A-2

Names: eukaryotic translation initiation factor 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213262.1 → NP_998427.1 eukaryotic translation initiation factor 5A-2

See identical proteins and their annotated locations for NP_998427.1

Status: PROVISIONAL

Source sequence(s)

BC066558

UniProtKB/TrEMBL

F6NMJ5, F6P0E4, Q7ZUP4

Related

ENSDARP00000073095.4, ENSDART00000078634.7

Conserved Domains (2) summary

PLN03107
Location:1 → 151

PLN03107; eukaryotic translation initiation factor 5A; Provisional

cd04468
Location:85 → 153

S1_eIF5A; S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential ...