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    pno1 partner of NOB1 homolog [ Danio rerio (zebrafish) ]

    Gene ID: 393520, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pno1provided by ZNC
    Official Full Name
    partner of NOB1 homologprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1419
    See related
    Ensembl:ENSDARG00000008502 AllianceGenome:ZFIN:ZDB-GENE-040426-1419
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:65782; zgc:77265
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Predicted to be active in nucleus. Is expressed in immature eye; midbrain; myotome; retina; and somite. Orthologous to human PNO1 (partner of NOB1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pno1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (1125187..1130059, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (994896..999768, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene cannabinoid receptor interacting protein 1b Neighboring gene protein phosphatase 3, regulatory subunit B, alpha a Neighboring gene dynein axonemal assembly factor 10 Neighboring gene proteasome 20S subunit beta 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of a novel human RNA binding protein gene PNO1. Zhou GJ, et al. DNA Seq, 2004 Jun. PMID 15497447
    2. The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility. Fin L, et al. Sci Rep, 2017 Jul 7. PMID 28687732, Free PMC Article
    3. Characterization of bovine A20 gene: Expression mediated by NF-κB pathway in MDBK cells infected with bovine viral diarrhea virus-1. Fredericksen F, et al. Gene, 2016 May 1. PMID 26809100
    4. Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis. Recher G, et al. Development, 2013 Dec. PMID 24198278
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC65782

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein PNO1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200548.1 → NP_956842.2  RNA-binding protein PNO1

      Status: VALIDATED

      Source sequence(s)
      BC056522
      UniProtKB/Swiss-Prot
      Q6P0J4, Q6PHK2, Q6VEU3
      UniProtKB/TrEMBL
      F1RDN0
      Related
      ENSDARP00000004926.8, ENSDART00000010261.9
      Conserved Domains (2) summary
      smart00322
      Location:177 → 229
      KH; K homology RNA-binding domain
      COG1094
      Location:74 → 251
      Krr1; rRNA processing protein Krr1/Pno1, contains KH domain [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      1125187..1130059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6VEU3.2 GenPept UniProtKB/Swiss-Prot:Q6VEU3

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