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    wtap WT1 associated protein [ Danio rerio (zebrafish) ]

    Gene ID: 334058, updated on 9-Dec-2024

    Summary

    Official Symbol
    wtapprovided by ZNC
    Official Full Name
    WT1 associated proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5990
    See related
    Ensembl:ENSDARG00000042642 AllianceGenome:ZFIN:ZDB-GENE-030131-5990
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66202; wu:fi29a09
    Summary
    Acts upstream of or within regulation of apoptotic process. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nucleus. Is expressed in head. Orthologous to human WTAP (WT1 associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See wtap in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (30931414..30938187, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (31028535..31035367, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene kinesin family member 25 Neighboring gene acetyl-CoA acetyltransferase 2 Neighboring gene superoxide dismutase 2, mitochondrial Neighboring gene fibronectin type III domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of RNA N6-methyladenosine methyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing regulator WTAP
    Names
    Wilms tumor 1 associated protein
    Wilms' tumour 1-associating protein
    female-lethal(2)D homolog
    wilms tumor 1-associating protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199853.1NP_956147.1  pre-mRNA-splicing regulator WTAP

      See identical proteins and their annotated locations for NP_956147.1

      Status: PROVISIONAL

      Source sequence(s)
      BC055544
      UniProtKB/Swiss-Prot
      Q7SXL7
      Related
      ENSDARP00000062551.4, ENSDART00000062552.6
      Conserved Domains (1) summary
      pfam17098
      Location:1246
      Wtap; Pre-mRNA-splicing regulator WTAP

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      30931414..30938187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)