U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gcshb glycine cleavage system protein H (aminomethyl carrier), b [ Danio rerio (zebrafish) ]

    Gene ID: 436852, updated on 9-Dec-2024

    Summary

    Official Symbol
    gcshbprovided by ZNC
    Official Full Name
    glycine cleavage system protein H (aminomethyl carrier), bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-319
    See related
    Ensembl:ENSDARG00000105187 AllianceGenome:ZFIN:ZDB-GENE-040718-319
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92732; wu:fd56h06; zgc:110557
    Summary
    Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be part of glycine cleavage complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See gcshb in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (67451169..67463021)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (67227817..67239669)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene nuclear factor of activated T cells 5b Neighboring gene lysyl-tRNA synthetase 1 Neighboring gene small nucleolar RNA MBII-202 Neighboring gene small nucleolar RNA MBII-202 Neighboring gene ribosomal protein L13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in glycine decarboxylation via glycine cleavage system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within glycine decarboxylation via glycine cleavage system IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of glycine cleavage complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of glycine cleavage complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glycine cleavage system protein H (aminomethyl carrier), b
    Names
    mitochondrial glycine cleavage system H protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002579.1NP_001002579.1  glycine cleavage system protein H (aminomethyl carrier), b

      See identical proteins and their annotated locations for NP_001002579.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076212
      UniProtKB/TrEMBL
      A0A0R4IGT7, B2GTH2, Q6DGX4
      Related
      ENSDARP00000134597.1, ENSDART00000163840.2
      Conserved Domains (1) summary
      PRK01202
      Location:52171
      PRK01202; glycine cleavage system protein H; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      67451169..67463021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)