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    insyn1 inhibitory synaptic factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100003007, updated on 9-Dec-2024

    Summary

    Official Symbol
    insyn1provided by ZNC
    Official Full Name
    inhibitory synaptic factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8029
    See related
    Ensembl:ENSDARG00000026247 AllianceGenome:ZFIN:ZDB-GENE-030131-8029
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    insy1; fj47h06; wu:fj47h06; zgc:158302; si:dkey-105e17.1
    Summary
    Predicted to be involved in inhibitory postsynaptic potential. Predicted to be located in synapse. Predicted to be active in postsynaptic density. Orthologous to human INSYN1 (inhibitory synaptic factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See insyn1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (50276337..50356795)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (50279315..50360224)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 5b Neighboring gene lysyl oxidase-like 1 Neighboring gene CD276 molecule Neighboring gene uncharacterized LOC101884348 Neighboring gene uncharacterized LOC137488347 Neighboring gene ubiquitin-like 7b (bone marrow stromal cell-derived)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC158302, MGC174955

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in inhibitory postsynaptic potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    inhibitory synaptic factor 1
    Names
    UPF0583 protein C15orf59 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079949.2NP_001073418.1  inhibitory synaptic factor 1

      See identical proteins and their annotated locations for NP_001073418.1

      Status: PROVISIONAL

      Source sequence(s)
      BC127579
      UniProtKB/Swiss-Prot
      Q1L899
      Related
      ENSDARP00000013334.7, ENSDART00000014582.10
      Conserved Domains (1) summary
      pfam15252
      Location:48275
      DUF4589; Domain of unknown function (DUF4589)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      50276337..50356795
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173684.4XP_005173741.1  inhibitory synaptic factor 1 isoform X1

      See identical proteins and their annotated locations for XP_005173741.1

      UniProtKB/Swiss-Prot
      Q1L899
      Related
      ENSDARP00000143115.1, ENSDART00000140352.3
      Conserved Domains (1) summary
      pfam15252
      Location:48275
      DUF4589; Domain of unknown function (DUF4589)