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    gdap2 ganglioside induced differentiation associated protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 447824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gdap2provided by ZNC
    Official Full Name
    ganglioside induced differentiation associated protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-31
    See related
    Ensembl:ENSDARG00000021569 AllianceGenome:ZFIN:ZDB-GENE-040912-31
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc38e07; zgc:92235; wu:fc38e07
    Summary
    Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 27. Orthologous to human GDAP2 (ganglioside induced differentiation associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gdap2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (20806332..20853439, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (20995463..21042570, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene mannosidase, alpha, class 1A, member 2 Neighboring gene uncharacterized LOC137496469 Neighboring gene terminal nucleotidyltransferase 5C Neighboring gene WD repeat domain 3 Neighboring gene uncharacterized LOC137496517

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Costimulatory Function of Cd58/Cd2 Interaction in Adaptive Humoral Immunity in a Zebrafish Model. Shao T, et al. Front Immunol, 2018. PMID 29904386, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ganglioside-induced differentiation-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004563.1 → NP_001004563.1  ganglioside-induced differentiation-associated protein 2

      See identical proteins and their annotated locations for NP_001004563.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081629
      UniProtKB/Swiss-Prot
      Q66HX8
      Related
      ENSDARP00000030237.5, ENSDART00000028247.7
      Conserved Domains (3) summary
      COG2110
      Location:65 → 230
      YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
      cd02905
      Location:65 → 204
      Macro_GDAP2_like; Macro domain, GDAP2_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
      pfam13716
      Location:358 → 481
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      20806332..20853439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HX8.1 GenPept UniProtKB/Swiss-Prot:Q66HX8

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