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    • Showing Current items.

    nenf neudesin neurotrophic factor [ Danio rerio (zebrafish) ]

    Gene ID: 571299, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nenfprovided by ZNC
    Official Full Name
    neudesin neurotrophic factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-129
    See related
    Ensembl:ENSDARG00000040192 AllianceGenome:ZFIN:ZDB-GENE-050320-129
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sp2; wu:fa11a04; wu:fb73f07; zgc:112953; zgc:152703
    Summary
    Predicted to be active in endoplasmic reticulum and membrane. Orthologous to human NENF (neudesin neurotrophic factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nenf in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (45395846..45402960)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (45412594..45419708)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 106a Neighboring gene proton activated chloride channel 1 Neighboring gene T cell activation RhoGTPase activating protein a Neighboring gene ezrin a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of two kcnk3 genes from the Northern snakehead (Channa argus) for quantification of their transcriptions in response to fasting and refeeding. Wen ZY, et al. Gen Comp Endocrinol, 2019 Sep 15. PMID 31121162
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112953, MGC152703

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    neudesin
    Names
    neuron derived neurotrophic factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037704.2 → NP_001032793.2  neudesin precursor

      See identical proteins and their annotated locations for NP_001032793.2

      Status: VALIDATED

      Source sequence(s)
      AI545016, BX322589, EH553755, EH600280
      UniProtKB/TrEMBL
      Q08CU3
      Related
      ENSDARP00000058792.6, ENSDART00000058793.7
      Conserved Domains (1) summary
      pfam00173
      Location:32 → 87
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      45395846..45402960
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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