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    tspan7 tetraspanin 7 [ Danio rerio (zebrafish) ]

    Gene ID: 449539, updated on 9-Dec-2024

    Summary

    Official Symbol
    tspan7provided by ZNC
    Official Full Name
    tetraspanin 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040927-5
    See related
    Ensembl:ENSDARG00000008407 AllianceGenome:ZFIN:ZDB-GENE-040927-5
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tm4sf2b; tspan7b; zgc:92829; wu:fb53h11
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in basal plate midbrain region; nervous system; notochord; and pancreatic bud. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 58. Orthologous to human TSPAN7 (tetraspanin 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tspan7 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (11440705..11493236, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (11411023..11463554, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103909557 Neighboring gene MID1 interacting protein 1b Neighboring gene uncharacterized LOC137488910 Neighboring gene solute carrier family 26 member 11 Neighboring gene N-sulfoglucosamine sulfohydrolase (sulfamidase) Neighboring gene neuropeptide B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    tetraspanin-7
    Names
    tetraspanin 7b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130818.1NP_001124290.1  tetraspanin-7

      Status: PROVISIONAL

      Source sequence(s)
      CU459213
      UniProtKB/TrEMBL
      A0A8M1NIF9, B0VEQ2
      Related
      ENSDARP00000018179.8, ENSDART00000002691.9
      Conserved Domains (2) summary
      cd03161
      Location:110213
      TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:14239
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      11440705..11493236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)