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    rrbp1b ribosome binding protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 567029, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rrbp1bprovided by ZNC
    Official Full Name
    ribosome binding protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030429-36
    See related
    Ensembl:ENSDARG00000041703 AllianceGenome:ZFIN:ZDB-GENE-030429-36
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rrbp1; sb:cb489; wu:fc47a01
    Summary
    Predicted to act upstream of or within protein transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including axis; digestive system; ectoderm; hatching gland; and mesoderm. Orthologous to human RRBP1 (ribosome binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rrbp1b in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (25086921..25109867)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (25059297..25082243)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene double zinc ribbon and ankyrin repeat domains 1 Neighboring gene lysine acetyltransferase 14 Neighboring gene PET117 cytochrome c oxidase chaperone Neighboring gene si:dkeyp-20e4.8 Neighboring gene uncharacterized LOC108181182

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. eys (+/-) ; lrp5 (+/-) Zebrafish Reveals Lrp5 Can Be the Receptor of Retinol in the Visual Cycle. Takita S, et al. iScience, 2020 Dec 18. PMID 33251495, Free PMC Article
    2. Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Dickmeis T, et al. Genome Res, 2004 Feb. PMID 14718378, Free PMC Article
    3. Hepatic gene expression profiling using GeneChips in zebrafish exposed to 17alpha-methyldihydrotestosterone. Hoffmann JL, et al. Aquat Toxicol, 2008 Apr 28. PMID 18339436
    4. Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber. Takamiya M, et al. PLoS One, 2015. PMID 25692557, Free PMC Article
    5. Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Zeng S, et al. Gene, 2002 Jul 10. PMID 12234666

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC174456

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosome-binding protein 1b
    Names
    ribosome binding protein 1 homolog 180kDa (dog)
    ribosome binding protein 1 homolog b (dog)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199431.2 → NP_955463.2  ribosome-binding protein 1b

      Status: VALIDATED

      Source sequence(s)
      BX294165
      UniProtKB/TrEMBL
      A0A8M1PCX5, Q1LXR3
      Related
      ENSDARP00000061116.5, ENSDART00000061117.6
      Conserved Domains (3) summary
      pfam05104
      Location:33 → 188
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      pfam07851
      Location:423 → 517
      TMPIT; TMPIT-like protein
      cl19219
      Location:546 → 638
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      25086921..25109867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005174040.4 → XP_005174097.1  ribosome-binding protein 1b isoform X1

      UniProtKB/TrEMBL
      A0A0R4IGW7, A0A8M2BLC3
      Related
      ENSDARP00000133183.2, ENSDART00000158225.2
      Conserved Domains (4) summary
      COG4942
      Location:279 → 529
      EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
      pfam05104
      Location:33 → 188
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      pfam07851
      Location:423 → 517
      TMPIT; TMPIT-like protein
      cl19219
      Location:546 → 638
      DUF342; Protein of unknown function (DUF342)

    2. XM_005174041.5 → XP_005174098.1  ribosome-binding protein 1b isoform X2

      UniProtKB/TrEMBL
      A0A2R8QNM4, A0A8M2BLF7
      Related
      ENSDARP00000154666.1, ENSDART00000192114.1
      Conserved Domains (3) summary
      pfam05104
      Location:33 → 188
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      pfam07851
      Location:423 → 517
      TMPIT; TMPIT-like protein
      cl19219
      Location:546 → 638
      DUF342; Protein of unknown function (DUF342)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395353.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      255901..280955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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