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    slc25a20 solute carrier family 25 member 20 [ Danio rerio (zebrafish) ]

    Gene ID: 393833, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc25a20provided by ZNC
    Official Full Name
    solute carrier family 25 member 20provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1869
    See related
    Ensembl:ENSDARG00000040401 AllianceGenome:ZFIN:ZDB-GENE-040426-1869
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77760
    Summary
    Predicted to enable acyl carnitine transmembrane transporter activity. Predicted to be involved in carnitine transmembrane transport and mitochondrial transport. Predicted to be located in membrane. Predicted to be active in mitochondrial envelope. Is expressed in cardiac ventricle and visceral fat. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slc25a20 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (105376..109686)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (132347..136657)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor Neighboring gene NCK interacting protein with SH3 domain Neighboring gene protein kinase, cAMP-dependent, regulatory, type II, alpha, B Neighboring gene si:ch1073-335m2.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. Nath AK, et al. FASEB J, 2020 Jan. PMID 31914600, Free PMC Article
    2. Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)(2)D(3). Peng X, et al. Cell Rep, 2017 May 16. PMID 28514663
    3. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Fukuda R, et al. EMBO Rep, 2020 Aug 5. PMID 32648304, Free PMC Article
    4. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    5. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77760

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyl carnitine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carnitine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial carnitine/acylcarnitine carrier protein
    Names
    solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
    NP_957153.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200859.1 → NP_957153.1  mitochondrial carnitine/acylcarnitine carrier protein

      See identical proteins and their annotated locations for NP_957153.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062851
      UniProtKB/TrEMBL
      A0A8M1PDJ8, Q6P5K6
      Related
      ENSDARP00000059139.6, ENSDART00000059140.8
      Conserved Domains (2) summary
      PTZ00169
      Location:10 → 276
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:107 → 197
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      105376..109686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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