ablim1a actin binding LIM protein 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ablim1aprovided by ZNC
Official Full Name: actin binding LIM protein 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-080219-41
See related: Ensembl:ENSDARG00000060149 AllianceGenome:ZFIN:ZDB-GENE-080219-41
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ablim1; zgc:172321
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in cilium assembly and lamellipodium assembly. Predicted to act upstream of or within cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be active in stress fiber. Orthologous to human ABLIM1 (actin binding LIM protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (43507383..43599920, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (43373558..43470576, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cytoskeleton organization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: actin-binding LIM protein 1a

Names: actin-binding LIM protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114316.1 → NP_001107788.1 actin-binding LIM protein 1a

See identical proteins and their annotated locations for NP_001107788.1

Status: PROVISIONAL

Source sequence(s)

BC155652

UniProtKB/TrEMBL

A0A8M3AZG5, A9JRG6

Related

ENSDARP00000115616.1, ENSDART00000145705.3

Conserved Domains (6) summary

smart00153
Location:658 → 693

VHP; Villin headpiece domain

cd09327
Location:50 → 101

LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins

cd09328
Location:106 → 161

LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins

cd09329
Location:187 → 238

LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins

cd09330
Location:246 → 301

LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins

pfam16182
Location:311 → 657

AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007124.7 Reference GRCz11 Primary Assembly

Range

43507383..43599920 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068224875.1 → XP_068080976.1 actin-binding LIM protein 1a isoform X3
XM_068224873.1 → XP_068080974.1 actin-binding LIM protein 1a isoform X1

UniProtKB/TrEMBL

A0A8M3B896
XM_068224874.1 → XP_068080975.1 actin-binding LIM protein 1a isoform X2

UniProtKB/TrEMBL

A0A8M3B5I2
XM_017358665.3 → XP_017214154.1 actin-binding LIM protein 1a isoform X4

UniProtKB/TrEMBL

A0A8M6Z1J7, A0A8M6Z9H1