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    sypl2a synaptophysin-like 2a [ Danio rerio (zebrafish) ]

    Gene ID: 393640, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sypl2aprovided by ZNC
    Official Full Name
    synaptophysin-like 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1434
    See related
    Ensembl:ENSDARG00000055307 AllianceGenome:ZFIN:ZDB-GENE-040426-1434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sypl; zgc:65838; wu:fd54d09
    Summary
    Predicted to be located in membrane and synaptic vesicle. Predicted to be active in synaptic vesicle membrane. Is expressed in pronephric duct. Orthologous to several human genes including SYPL1 (synaptophysin like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See sypl2a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (36355314..36376073)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (36093331..36114090)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene sortilin 1a Neighboring gene uncharacterized LOC137490426 Neighboring gene proteasome 20S subunit alpha 5 Neighboring gene ataxin 7-like 2a Neighboring gene cytochrome b561 family, member D1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Targeted expression of human MYCN selectively causes pancreatic neuroendocrine tumors in transgenic zebrafish. Yang HW, et al. Cancer Res, 2004 Oct 15. PMID 15492244
    2. Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates. Kassahn KS, et al. Genome Res, 2009 Aug. PMID 19439512, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC65838

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    synaptophysin-like protein 2a
    Names
    synaptophysin-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200667.2 → NP_956961.2  synaptophysin-like protein 2a

      Status: VALIDATED

      Source sequence(s)
      BX248230, EH441250
      UniProtKB/TrEMBL
      A0A8M1PFK8, F1Q7F9
      Related
      ENSDARP00000115067.1, ENSDART00000145427.3
      Conserved Domains (1) summary
      pfam01284
      Location:17 → 211
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      36355314..36376073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_011017119.1 RNA Sequence

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394825.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      307711..328470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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