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    klhl17 kelch-like family member 17 [ Danio rerio (zebrafish) ]

    Gene ID: 336187, updated on 9-Dec-2024

    Summary

    Official Symbol
    klhl17provided by ZNC
    Official Full Name
    kelch-like family member 17provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8131
    See related
    Ensembl:ENSDARG00000037324 AllianceGenome:ZFIN:ZDB-GENE-030131-8131
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj54g09; si:dkey-98j1.3
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in telencephalon. Orthologous to human KLHL17 (kelch like family member 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See klhl17 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (23182047..23214599)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (23255486..23288048)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene sterile alpha motif domain containing 11 Neighboring gene NOC2-like nucleolar associated transcriptional repressor Neighboring gene pleckstrin homology domain containing, family N member 1 Neighboring gene PPARGC1 and ESRR induced regulator, muscle 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    kelch-like protein 17
    Names
    kelch-like 17

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      23182047..23214599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003201200.6XP_003201248.1  kelch-like protein 17

      See identical proteins and their annotated locations for XP_003201248.1

      UniProtKB/TrEMBL
      A0A8M2B929, E7FB30
      Related
      ENSDARP00000119330.1, ENSDART00000137353.3
      Conserved Domains (4) summary
      smart00612
      Location:528572
      Kelch; Kelch domain
      PHA03098
      Location:41507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:375418
      Kelch; KELCH repeat [structural motif]
      cd18246
      Location:2140
      BTB_POZ_KLHL17_actinfilin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 17 (KLHL17)
    2. XM_005162205.5XP_005162262.1  kelch-like protein 17

      See identical proteins and their annotated locations for XP_005162262.1

      UniProtKB/TrEMBL
      A0A8M2B929, E7FB30
      Related
      ENSDARP00000156064.1, ENSDART00000184920.1
      Conserved Domains (4) summary
      smart00612
      Location:528572
      Kelch; Kelch domain
      PHA03098
      Location:41507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:375418
      Kelch; KELCH repeat [structural motif]
      cd18246
      Location:2140
      BTB_POZ_KLHL17_actinfilin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 17 (KLHL17)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395148.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      104471..137023
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473681.2XP_021329356.1  kelch-like protein 17

      UniProtKB/TrEMBL
      A0A8M2B929, E7FB30
      Conserved Domains (4) summary
      smart00612
      Location:528572
      Kelch; Kelch domain
      PHA03098
      Location:41507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:375418
      Kelch; KELCH repeat [structural motif]
      cd18246
      Location:2140
      BTB_POZ_KLHL17_actinfilin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 17 (KLHL17)
    2. XM_021473682.2XP_021329357.1  kelch-like protein 17

      UniProtKB/TrEMBL
      A0A8M2B929, E7FB30
      Conserved Domains (4) summary
      smart00612
      Location:528572
      Kelch; Kelch domain
      PHA03098
      Location:41507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:375418
      Kelch; KELCH repeat [structural motif]
      cd18246
      Location:2140
      BTB_POZ_KLHL17_actinfilin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 17 (KLHL17)