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    glipr2 GLI pathogenesis-related 2 [ Danio rerio (zebrafish) ]

    Gene ID: 325699, updated on 9-Dec-2024

    Summary

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    Official Symbol
    glipr2provided by ZNC
    Official Full Name
    GLI pathogenesis-related 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4424
    See related
    Ensembl:ENSDARG00000041724 AllianceGenome:ZFIN:ZDB-GENE-030131-4424
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd05a10; im:6795575; wu:fd05a10; si:dkey-2n12.1
    Summary
    Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blood cell and vascular endothelium. Orthologous to human GLIPR2 (GLI pathogenesis related 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See glipr2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (33028079..33039783, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (32427763..32439570, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene LIM domain only 4a Neighboring gene zgc:55461 Neighboring gene neuropeptide FF receptor 2 Neighboring gene uncharacterized LOC100001344 Neighboring gene KN motif and ankyrin repeat domains 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development. Hensley MR, et al. Sci Rep, 2016 Jun 13. PMID 27292017, Free PMC Article
    2. Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development. Tallafuss A, et al. Gene Expr Patterns, 2006 Jun. PMID 16448862
    3. Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation. Xue Y, et al. Dev Biol, 2015 Jul 15. PMID 26015096
    4. Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Cannon JE, et al. Mech Dev, 2013 Feb. PMID 23072875, Free PMC Article
    5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GLI pathogenesis-related 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001423664.1 → NP_001410593.1  GLI pathogenesis-related 2

      Status: VALIDATED

      Source sequence(s)
      CR855258
      UniProtKB/TrEMBL
      A0A8M9PR01, A0A8M9QEP8, A2CF32
      Related
      ENSDARP00000118616.1, ENSDART00000141361.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      33028079..33039783 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476526.2 → XP_021332201.1  GLI pathogenesis-related 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PEW6, A0A8M9PR01
      Conserved Domains (3) summary
      cd05382
      Location:126 → 256
      SCP_GAPR-1_like; SCP-like extracellular protein domain, golgi-associated plant pathogenesis related protein (GAPR)-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory ...
      cl00133
      Location:2 → 65
      SCP; SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in cell ...
      cl27373
      Location:223 → 329
      PapD_C; Pili assembly chaperone PapD, C-terminal domain

    2. XM_068221100.1 → XP_068077201.1  GLI pathogenesis-related 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PR01

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394587.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      128131..140189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395240.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      299117..310817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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