avp arginine vasopressin [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: avpprovided by ZNC
Official Full Name: arginine vasopressinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030407-2
See related: Ensembl:ENSDARG00000058567 AllianceGenome:ZFIN:ZDB-GENE-030407-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: avpl; vsnp; VT-NP
Summary: Predicted to enable neuropeptide hormone activity. Located in axon hillock. Is expressed in female organism; male organism; and nervous system. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Orthologous to human AVP (arginine vasopressin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (1148876..1157380)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (1083133..1091637)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results describe the ontogeny of vasotocin-expressing cells in zebrafish, and the selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area.
Title: Ontogeny of vasotocin-expressing cells in zebrafish: selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables neurohypophyseal hormone activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide hormone activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in axon hillock	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
is_active_in secretory granule	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: vasopressin-neurophysin 2-copeptin

Names: AVT; arginine vasotocin; vasotocin neurophysin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.