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    tmsb thymosin, beta [ Danio rerio (zebrafish) ]

    Gene ID: 402820, updated on 9-Dec-2024

    Summary

    Official Symbol
    tmsbprovided by ZNC
    Official Full Name
    thymosin, betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050307-5
    See related
    Ensembl:ENSDARG00000054911 AllianceGenome:ZFIN:ZDB-GENE-050307-5
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7149936; zgc:136504
    Summary
    Predicted to enable actin monomer binding activity. Acts upstream of or within induction of bacterial agglutination and regulation of inflammatory response to wounding. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Is expressed in several structures, including gill; integument; liver; pleuroperitoneal region; and thymus. Orthologous to human TMSB10 (thymosin beta 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tmsb in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26389429..26392044)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26352734..26355349)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488818 Neighboring gene glutamate receptor, ionotropic, AMPA 1b Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene eukaryotic translation initiation factor 4E binding protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC136504

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin monomer binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thymosin beta
    Names
    beta-thymosin
    zTB10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205581.1NP_991144.1  thymosin beta

      See identical proteins and their annotated locations for NP_991144.1

      Status: PROVISIONAL

      Source sequence(s)
      AF006831
      UniProtKB/Swiss-Prot
      Q9W7M8
      UniProtKB/TrEMBL
      Q1RM34
      Related
      ENSDARP00000071665.5, ENSDART00000077197.6
      Conserved Domains (1) summary
      pfam01290
      Location:340
      Thymosin; Thymosin beta-4 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      26389429..26392044
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)