isoc2 isochorismatase domain containing 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: isoc2provided by ZNC
Official Full Name: isochorismatase domain containing 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-070518-1
See related: Ensembl:ENSDARG00000013371 AllianceGenome:ZFIN:ZDB-GENE-070518-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7143522; zgc:109735
Summary: Predicted to be active in cytoplasm. Orthologous to human ISOC2 (isochorismatase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (12793911..12809886, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (12903791..12919766, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: isochorismatase domain-containing protein 2

Names: isochorismatase domain-containing protein 2, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079953.2 → NP_001073422.2 isochorismatase domain-containing protein 2

See identical proteins and their annotated locations for NP_001073422.2

Status: VALIDATED

Source sequence(s)

BC125848, CR848818

UniProtKB/Swiss-Prot

A0JME6

Related

ENSDARP00000022030.7, ENSDART00000007842.9

Conserved Domains (1) summary

cd01012
Location:13 → 167

YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...