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    ankrd22 ankyrin repeat domain 22 [ Danio rerio (zebrafish) ]

    Gene ID: 393244, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ankrd22provided by ZNC
    Official Full Name
    ankyrin repeat domain 22provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1120
    See related
    Ensembl:ENSDARG00000002298 AllianceGenome:ZFIN:ZDB-GENE-040426-1120
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56706
    Summary
    Predicted to be located in membrane. Orthologous to human ANKRD22 (ankyrin repeat domain 22). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ankrd22 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (17154778..17158622)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (17032904..17036748)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene actin alpha 2, smooth muscle Neighboring gene STAM binding protein-like 1 Neighboring gene lipase, gastric Neighboring gene renalase, FAD-dependent amine oxidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. Pereiro P, et al. Antiviral Res, 2017 Sep. PMID 28789986
    2. A new evolutionary model for the vertebrate actin family including two novel groups. Witjes L, et al. Mol Phylogenet Evol, 2019 Dec. PMID 31560986
    3. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56706

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200274.1 → NP_956568.1  ankyrin repeat domain-containing protein 22

      See identical proteins and their annotated locations for NP_956568.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049065
      UniProtKB/TrEMBL
      Q7ZUF7
      Related
      ENSDARP00000012738.3, ENSDART00000028003.5
      Conserved Domains (4) summary
      cd00204
      Location:33 → 187
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:44 → 165
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:5 → 60
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:40 → 70
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      17154778..17158622
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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