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    ndst2b N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b [ Danio rerio (zebrafish) ]

    Gene ID: 798226, updated on 9-Dec-2024

    Summary

    Official Symbol
    ndst2bprovided by ZNC
    Official Full Name
    N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100430-2
    See related
    Ensembl:ENSDARG00000060678 AllianceGenome:ZFIN:ZDB-GENE-100430-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ndst2
    Summary
    Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and hydrolase activity. Predicted to be involved in heparin biosynthetic process. Predicted to be located in membrane. Is expressed in alar plate midbrain region; brain; midbrain neural rod; optic tectum; and rhombomere. Orthologous to human NDST2 (N-deacetylase and N-sulfotransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ndst2b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (35203144..35341611)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (35101980..35238824)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene si:ch73-127m5.2 Neighboring gene si:ch73-127m5.1 Neighboring gene cannabinoid receptor 2-like Neighboring gene calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 Neighboring gene SEC24 homolog C, COPII coat complex component

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables [heparan sulfate]-glucosamine N-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables [heparan sulfate]-glucosamine N-sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables deacetylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in heparin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
    Names
    N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
    XP_021336066.1
    XP_068080907.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      35203144..35341611
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480391.2XP_021336066.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

      UniProtKB/TrEMBL
      A0A8M2B2F8, E7F995, U3JAI5
      Related
      ENSDARP00000127253.1, ENSDART00000153022.3
      Conserved Domains (2) summary
      pfam00685
      Location:613864
      Sulfotransfer_1; Sulfotransferase domain
      pfam12062
      Location:25524
      HSNSD; heparan sulfate-N-deacetylase
    2. XM_068224806.1XP_068080907.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

      UniProtKB/TrEMBL
      A0A8M2B2F8, E7F995, U3JAI5
      Related
      ENSDARP00000143988.1, ENSDART00000178663.2