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    slc20a2 solute carrier family 20 member 2 [ Danio rerio (zebrafish) ]

    Gene ID: 558346, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc20a2provided by ZNC
    Official Full Name
    solute carrier family 20 member 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-828
    See related
    Ensembl:ENSDARG00000060796 AllianceGenome:ZFIN:ZDB-GENE-060929-828
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi23g11; wu:fi23g11; zgc:152990
    Summary
    Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to act upstream of or within phosphate ion transport and sodium ion transport. Predicted to be located in apical plasma membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A2 (solute carrier family 20 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slc20a2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (29770090..29851636, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (29760860..29842488, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene tetraspanin 36 Neighboring gene mitogen-activated protein kinase 4 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene excision repair cross-complementation group 6-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparison between Timelines of Transcriptional Regulation in Mammals, Birds, and Teleost Fish Somitogenesis. Fongang B, et al. PLoS One, 2016. PMID 27192554, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC152990

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphate ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sodium-dependent phosphate transporter 2
    Names
    solute carrier family 20 (phosphate transporter), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077546.1 → NP_001071014.1  sodium-dependent phosphate transporter 2

      See identical proteins and their annotated locations for NP_001071014.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124206
      UniProtKB/TrEMBL
      Q08CK2
      Conserved Domains (2) summary
      COG0306
      Location:7 → 488
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:382 → 480
      PHO4; Phosphate transporter family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      29770090..29851636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005167168.5 → XP_005167225.1  sodium-dependent phosphate transporter 2 isoform X1

      See identical proteins and their annotated locations for XP_005167225.1

      UniProtKB/TrEMBL
      A0A0R4ITC6, A0A8M9Q9Q1, F1Q836, F8W3B1
      Related
      ENSDARP00000124436.1, ENSDART00000149297.3
      Conserved Domains (2) summary
      COG0306
      Location:7 → 225
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:501 → 647
      PHO4; Phosphate transporter family

    2. XM_005167171.5 → XP_005167228.1  sodium-dependent phosphate transporter 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BEK1
      Conserved Domains (2) summary
      COG0306
      Location:485 → 654
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:548 → 646
      PHO4; Phosphate transporter family

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395274.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      269922..313899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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