cnot10 CCR4-NOT transcription complex, subunit 10 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cnot10provided by ZNC
Official Full Name: CCR4-NOT transcription complex, subunit 10provided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-368
See related: Ensembl:ENSDARG00000058528 AllianceGenome:ZFIN:ZDB-GENE-060929-368
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7139356; zgc:152939
Summary: Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT10 (CCR4-NOT transcription complex subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (7703534..7730593)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (7786423..7813522)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in mRNA catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of translation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info
involved_in regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CCR4-NOT complex	IBA Inferred from Biological aspect of Ancestor more info
part_of CCR4-NOT complex	IEA Inferred from Electronic Annotation more info
part_of CCR4-NOT complex	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CCR4-NOT transcription complex subunit 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077532.2 → NP_001071000.1 CCR4-NOT transcription complex subunit 10

See identical proteins and their annotated locations for NP_001071000.1

Status: PROVISIONAL

Source sequence(s)

BC124182

UniProtKB/Swiss-Prot

Q08CL8, Q5BLH2

Related

ENSDARP00000075848.4, ENSDART00000081407.6

Conserved Domains (3) summary

sd00006
Location:170 → 195

TPR; TPR repeat [structural motif]

pfam00515
Location:170 → 197

TPR_1; Tetratricopeptide repeat

pfam13414
Location:123 → 195

TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

7703534..7730593

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068213947.1 → XP_068070048.1 CCR4-NOT transcription complex subunit 10 isoform X5
XM_068213948.1 → XP_068070049.1 CCR4-NOT transcription complex subunit 10 isoform X6

Related

ENSDARP00000124553.1, ENSDART00000149752.3
XM_005157863.5 → XP_005157920.1 CCR4-NOT transcription complex subunit 10 isoform X1

UniProtKB/TrEMBL

A0A8M2B486

Conserved Domains (3) summary

sd00006
Location:295 → 320

TPR; TPR repeat [structural motif]

pfam00515
Location:295 → 322

TPR_1; Tetratricopeptide repeat

pfam13414
Location:248 → 320

TPR_11; TPR repeat
XM_068213945.1 → XP_068070046.1 CCR4-NOT transcription complex subunit 10 isoform X3
XM_005157862.5 → XP_005157919.1 CCR4-NOT transcription complex subunit 10 isoform X2

UniProtKB/TrEMBL

A0A8M2B459, E7FA32

Related

ENSDARP00000106673.1, ENSDART00000125111.3

Conserved Domains (3) summary

sd00006
Location:294 → 319

TPR; TPR repeat [structural motif]

pfam00515
Location:294 → 321

TPR_1; Tetratricopeptide repeat

pfam13414
Location:247 → 319

TPR_11; TPR repeat
XM_068213946.1 → XP_068070047.1 CCR4-NOT transcription complex subunit 10 isoform X4