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    mgst3a microsomal glutathione S-transferase 3a [ Danio rerio (zebrafish) ]

    Gene ID: 406736, updated on 9-Dec-2024

    Summary

    Official Symbol
    mgst3aprovided by ZNC
    Official Full Name
    microsomal glutathione S-transferase 3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2767
    See related
    Ensembl:ENSDARG00000102744 AllianceGenome:ZFIN:ZDB-GENE-040426-2767
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mgst3; zgc:56518
    Summary
    Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in leukotriene metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Is expressed in several structures, including alar plate midbrain region; brain; digestive system; immature eye; and pleuroperitoneal region. Orthologous to human MGST3 (microsomal glutathione S-transferase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mgst3a in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (48579535..48604653, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (48757462..48773474, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene insulinoma-associated 1a Neighboring gene meiotic double-stranded break formation protein 1 Neighboring gene cilia and flagella associated protein 61 Neighboring gene uncharacterized LOC110438202 Neighboring gene U5 spliceosomal RNA Neighboring gene U5 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glutathione peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in leukotriene metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    microsomal glutathione S-transferase 3a
    Names
    microsomal glutathione S-transferase 3
    NP_998592.1
    XP_005160934.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213427.1NP_998592.1  microsomal glutathione S-transferase 3a

      See identical proteins and their annotated locations for NP_998592.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049037
      UniProtKB/TrEMBL
      A0A8N1TYQ7, Q7ZUH8
      Related
      ENSDARP00000133484.1, ENSDART00000170894.2
      Conserved Domains (1) summary
      pfam01124
      Location:11130
      MAPEG; MAPEG family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      48579535..48604653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160877.3XP_005160934.1  microsomal glutathione S-transferase 3a isoform X1

      See identical proteins and their annotated locations for XP_005160934.1

      UniProtKB/TrEMBL
      A0A8N1TYQ7, Q7ZUH8
      Related
      ENSDARP00000137323.1, ENSDART00000157871.2
      Conserved Domains (1) summary
      pfam01124
      Location:11130
      MAPEG; MAPEG family