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    ifrd2 interferon-related developmental regulator 2 [ Danio rerio (zebrafish) ]

    Gene ID: 445227, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ifrd2provided by ZNC
    Official Full Name
    interferon-related developmental regulator 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-140
    See related
    Ensembl:ENSDARG00000036811 AllianceGenome:ZFIN:ZDB-GENE-040801-140
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb94c05; fc05c10; sb:cb936; wu:fb94c05; wu:fc05c10; zgc:100956
    Summary
    Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; pectoral fin bud; and segmental plate. Orthologous to human IFRD2 (interferon related developmental regulator 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ifrd2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (26410200..26427315)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (26391031..26408172)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:dkey-20d21.12 Neighboring gene hyaluronidase 3 Neighboring gene aminomethyltransferase Neighboring gene zgc:136971 Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Semaphorin/neuropilin binding specificities are stable over 400 million years of evolution. He Z, et al. Biochem Biophys Res Commun, 2019 Sep 10. PMID 31349972, Free PMC Article
    2. Activation of cytokine expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus-infected cells. Wang WL, et al. Fish Shellfish Immunol, 2011 Jul. PMID 21272652
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    interferon-related developmental regulator 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003621.1 → NP_001003621.1  interferon-related developmental regulator 2

      See identical proteins and their annotated locations for NP_001003621.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078215
      UniProtKB/TrEMBL
      Q6DC68
      Related
      ENSDARP00000053446.2, ENSDART00000053447.3
      Conserved Domains (2) summary
      pfam04836
      Location:380 → 432
      IFRD_C; Interferon-related protein conserved region
      pfam05004
      Location:28 → 334
      IFRD; Interferon-related developmental regulator (IFRD)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      26410200..26427315
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005167029.5 → XP_005167086.1  interferon-related developmental regulator 2 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IV16, A0A8M2BEC4
      Related
      ENSDARP00000140957.1, ENSDART00000168780.2
      Conserved Domains (2) summary
      pfam04836
      Location:400 → 452
      IFRD_C; Interferon-related protein conserved region
      pfam05004
      Location:48 → 354
      IFRD; Interferon-related developmental regulator (IFRD)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394726.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      9745..26856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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