U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    eif3g eukaryotic translation initiation factor 3, subunit G [ Danio rerio (zebrafish) ]

    Gene ID: 393974, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    eif3gprovided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Gprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1076
    See related
    Ensembl:ENSDARG00000016889 AllianceGenome:ZFIN:ZDB-GENE-040426-1076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    eif3s4; zgc:56553
    Summary
    Predicted to enable RNA binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3G (eukaryotic translation initiation factor 3 subunit G). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See eif3g in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (54582032..54589823)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (54327430..54335221)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene peter pan homolog Neighboring gene purinergic receptor P2Y11 Neighboring gene DNA (cytosine-5-)-methyltransferase 1 Neighboring gene sphingosine-1-phosphate receptor 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins. von Moeller H, et al. Nucleic Acids Res, 2013 Sep. PMID 23804756, Free PMC Article
    2. Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Anderson RM, et al. Dev Biol, 2009 Oct 1. PMID 19631206, Free PMC Article
    3. Transcriptomic profile of early zebrafish PGCs by single cell sequencing. Zhang X, et al. PLoS One, 2019. PMID 31412047, Free PMC Article
    4. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Liu X, et al. J Hematol Oncol, 2015 Feb 22. PMID 25886310, Free PMC Article
    5. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC56553

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in formation of cytoplasmic translation initiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic 43S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic 48S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    eukaryotic translation initiation factor 3 subunit G
    Names
    eukaryotic translation initiation factor 3, subunit 4 delta

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200999.1 → NP_957293.1  eukaryotic translation initiation factor 3 subunit G

      See identical proteins and their annotated locations for NP_957293.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049046
      UniProtKB/Swiss-Prot
      Q6DRC4
      Related
      ENSDARP00000027672.6, ENSDART00000018071.9
      Conserved Domains (3) summary
      COG0724
      Location:172 → 293
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12933
      Location:35 → 147
      eIF3G; eIF3G domain found in eukaryotic translation initiation factor 3 subunit G (eIF-3G) and similar proteins
      cd12408
      Location:213 → 289
      RRM_eIF3G_like; RNA recognition motif in eukaryotic translation initiation factor 3 subunit G (eIF-3G) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      54582032..54589823
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DRC4.1 GenPept UniProtKB/Swiss-Prot:Q6DRC4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.