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    rbm15 RNA binding motif protein 15 [ Danio rerio (zebrafish) ]

    Gene ID: 798517, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rbm15provided by ZNC
    Official Full Name
    RNA binding motif protein 15provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041008-192
    See related
    AllianceGenome:ZFIN:ZDB-GENE-041008-192
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7139999
    Summary
    Predicted to enable mRNA binding activity. Acts upstream of or within liver development. Predicted to be active in nucleus. Is expressed in liver and liver primordium. Orthologous to human RBM15 (RNA binding motif protein 15). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: only annotated on alternate loci in reference assembly
    Orthologs
    all
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    Genomic context

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    See rbm15 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 Unlocalized Scaffold (ALT_DRER_TU_1) NW_018394725.1 (307497..312168, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (24767335..24772088, complement)

    NW_018394725.1Genomic Context describing neighboring genes Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Neighboring gene solute carrier family 16 member 4 Neighboring gene uncharacterized LOC137490327 Neighboring gene ALX homeobox 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish. Hu L, et al. J Biol Chem, 2020 Aug 14. PMID 32518161, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish.
      Title: Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within liver development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative RNA-binding protein 15; RNA-binding protein 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394725.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      307497..312168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001335784.8 → XP_001335820.1  RNA-binding protein 15

      UniProtKB/TrEMBL
      A0A8M1PS32, F1RCY7
      Conserved Domains (5) summary
      cd12553
      Location:124 → 201
      RRM1_RBM15; RNA recognition motif 1 in vertebrate RNA binding motif protein 15 (RBM15)
      cd12555
      Location:297 → 383
      RRM2_RBM15; RNA recognition motif 2 in vertebrate RNA binding motif protein 15 (RBM15)
      cd12557
      Location:386 → 458
      RRM3_RBM15; RNA recognition motif 3 in vertebrate RNA binding motif protein 15 (RBM15)
      pfam07744
      Location:684 → 850
      SPOC; SPOC domain
      cl28033
      Location:495 → 685
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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