rpl10a ribosomal protein L10a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rpl10aprovided by ZNC
Official Full Name: ribosomal protein L10aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2025
See related: Ensembl:ENSDARG00000042905 AllianceGenome:ZFIN:ZDB-GENE-030131-2025
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73082; zgc:86881; wu:fb94f08
Summary: Predicted to enable RNA binding activity. Acts upstream of or within T cell differentiation in thymus; chordate embryonic development; and hemoglobin biosynthetic process. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL10A (ribosomal protein L10a). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (23738140..23742985)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (23716901..23721746)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development.
Title: Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development.

Submit: New GeneRIF Correction

General gene information

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Markers

fd36d04.y1 (e-PCR)
- UniSTS:195418

fb94f08.x1 (e-PCR)
- UniSTS:191837

fb94f08.x1 (e-PCR)
- UniSTS:191838

fb13h04.x1 (e-PCR)
- UniSTS:190119

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within T cell differentiation in thymus	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within chordate embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within hemoglobin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of large ribosomal subunit	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: large ribosomal subunit protein uL1

Names: 60S ribosomal protein L10a

NP_955930.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199636.1 → NP_955930.1 large ribosomal subunit protein uL1

See identical proteins and their annotated locations for NP_955930.1

Status: PROVISIONAL

Source sequence(s)

BC059454

UniProtKB/Swiss-Prot

Q6IQA0, Q6PC69

Related

ENSDARP00000062982.5, ENSDART00000062983.7

Conserved Domains (1) summary

cl00322
Location:1 → 216

Ribosomal_L1; Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds ...