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    stk17a serine/threonine kinase 17a [ Danio rerio (zebrafish) ]

    Gene ID: 327345, updated on 9-Dec-2024

    Summary

    Official Symbol
    stk17aprovided by ZNC
    Official Full Name
    serine/threonine kinase 17aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5556
    See related
    Ensembl:ENSDARG00000074715 AllianceGenome:ZFIN:ZDB-GENE-030131-5556
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi04a03; wu:fi04a03; zgc:158623
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and positive regulation of apoptotic process. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Orthologous to human STK17A (serine/threonine kinase 17a). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See stk17a in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (744713..788778)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (192939..237004)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene V-set and transmembrane domain containing 2A Neighboring gene E3 ubiquitin-protein ligase HECW1 Neighboring gene piezo-type mechanosensitive ion channel component 2 Neighboring gene inositol monophosphatase 2 Neighboring gene N-ethylmaleimide-sensitive factor attachment protein, gamma a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase 17A
    NP_001082806.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089337.2NP_001082806.2  serine/threonine-protein kinase 17A

      Status: VALIDATED

      Source sequence(s)
      CABZ01114063, CABZ01114064
      UniProtKB/TrEMBL
      A4IFW6
      Related
      ENSDARP00000067763.4, ENSDART00000067764.7

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      744713..788778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)