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    pcgf6 polycomb group ring finger 6 [ Danio rerio (zebrafish) ]

    Gene ID: 555238, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pcgf6provided by ZNC
    Official Full Name
    polycomb group ring finger 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-178
    See related
    Ensembl:ENSDARG00000069681 AllianceGenome:ZFIN:ZDB-GENE-060526-178
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7144322; si:ch211-67n3.7
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of PRC1 complex. Is expressed in gonad; nervous system; and pharyngeal arch. Orthologous to human PCGF6 (polycomb group ring finger 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pcgf6 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (28682625..28689684, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (28552175..28559234, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene 5'-nucleotidase, cytosolic IIa Neighboring gene internexin neuronal intermediate filament protein, alpha a Neighboring gene RNA polymerase I and III subunit C Neighboring gene LIM domain binding 1a Neighboring gene small nucleolar RNA SNORA13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging. Dupret B, et al. PLoS One, 2016. PMID 27442247, Free PMC Article
    2. Gene expression profile of a selection of Polycomb Group genes during zebrafish embryonic and germ line development. Chrispijn ND, et al. PLoS One, 2018. PMID 29985950, Free PMC Article
    3. The zebrafish genes encoding the Polycomb repressive complex (PRC) 1. Le Faou P, et al. Gene, 2011 Apr 1. PMID 21195142
    4. Evolution of developmental regulation in the vertebrate FgfD subfamily. Jovelin R, et al. J Exp Zool B Mol Dev Evol, 2010 Jan 15. PMID 19562753, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC162242

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of PRC1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    polycomb group RING finger protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089369.1 → NP_001082838.1  polycomb group RING finger protein 6

      See identical proteins and their annotated locations for NP_001082838.1

      Status: PROVISIONAL

      Source sequence(s)
      BC139554
      UniProtKB/TrEMBL
      A2ATX3, A4QNX1
      Related
      ENSDARP00000092355.3, ENSDART00000101582.5
      Conserved Domains (2) summary
      pfam00097
      Location:60 → 98
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)
      pfam16207
      Location:196 → 253
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      28682625..28689684 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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