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    spout1 SPOUT domain containing methyltransferase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 447888, updated on 9-Dec-2024

    Summary

    Official Symbol
    spout1provided by ZNC
    Official Full Name
    SPOUT domain containing methyltransferase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-53
    See related
    Ensembl:ENSDARG00000019707 AllianceGenome:ZFIN:ZDB-GENE-040912-53
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb90; sb:cb90; zgc:101748
    Summary
    Predicted to enable miRNA binding activity. Predicted to be involved in maintenance of centrosome location and miRNA processing. Predicted to act upstream of or within methylation. Predicted to be active in kinetochore; mitotic spindle; and spindle pole centrosome. Is expressed in several structures, including blood; central nervous system; neural tube; optic vesicle; and tail bud. Orthologous to human SPOUT1 (SPOUT domain containing methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See spout1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (3796659..3814491)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (3645000..3663070)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene torsin family 1 Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae) Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables miRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in maintenance of centrosome location IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in miRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitotic spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in spindle pole centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative methyltransferase C9orf114 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004627.1NP_001004627.1  putative methyltransferase C9orf114 homolog

      See identical proteins and their annotated locations for NP_001004627.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081398
      UniProtKB/TrEMBL
      A0A8M1N2E4, Q66ID3
      Related
      ENSDARP00000090309.3, ENSDART00000099535.5
      Conserved Domains (1) summary
      pfam02598
      Location:78367
      Methyltrn_RNA_3; Putative RNA methyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      3796659..3814491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)