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    pih1d1 PIH1 domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 553260, updated on 9-Dec-2024

    Summary

    Official Symbol
    pih1d1provided by ZNC
    Official Full Name
    PIH1 domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-147
    See related
    Ensembl:ENSDARG00000037955 AllianceGenome:ZFIN:ZDB-GENE-050309-147
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7150545
    Summary
    Acts upstream of or within axonemal dynein complex assembly. Predicted to be located in nucleus. Predicted to be part of R2TP complex and ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in Kupffer's vesicle; floor plate; otic vesicle; and pronephric duct. Orthologous to human PIH1D1 (PIH1 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See pih1d1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (32172534..32180829, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (32040820..32049115, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin Va Neighboring gene troponin T type 1 (skeletal, slow) Neighboring gene uncharacterized LOC100534715 Neighboring gene carnitine palmitoyltransferase 1A2b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within axonemal dynein complex assembly PubMed 
    involved_in box C/D snoRNP assembly  
    involved_in rRNA processing  
    Component Evidence Code Pubs
    part_of R2TP complex  
    is_active_in cytoplasm  
    located_in nucleus  
    located_in nucleus  
    part_of ribonucleoprotein complex  

    General protein information

    Preferred Names
    PIH1 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159928.1 → NP_001153400.1  PIH1 domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      BX511021, EH536839, EH539446
      UniProtKB/Swiss-Prot
      A1L208, Q0V938, Q1RM55, Q4V8T6, Q5XJL7
      UniProtKB/TrEMBL
      A0A8M1NRJ1
      Related
      ENSDARP00000055307.3, ENSDART00000055308.5
      Conserved Domains (1) summary
      cl00175
      Location:34 → 290
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      32172534..32180829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009299539.4 → XP_009297814.1  PIH1 domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      A1L208, Q0V938, Q1RM55, Q4V8T6, Q5XJL7
      UniProtKB/TrEMBL
      A0A8M3AQY5
      Conserved Domains (1) summary
      cl00175
      Location:33 → 289
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
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