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    prdx5 peroxiredoxin 5 [ Danio rerio (zebrafish) ]

    Gene ID: 554105, updated on 9-Dec-2024

    Summary

    Official Symbol
    prdx5provided by ZNC
    Official Full Name
    peroxiredoxin 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-159
    See related
    Ensembl:ENSDARG00000055064 AllianceGenome:ZFIN:ZDB-GENE-050522-159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112318
    Summary
    Predicted to enable thioredoxin peroxidase activity. Acts upstream of or within fin regeneration. Predicted to be located in peroxisomal matrix. Predicted to be active in mitochondrion and peroxisome. Is expressed in several structures, including alar plate midbrain region; macrophage; optic vesicle; pronephric duct; and sensory system. Orthologous to human PRDX5 (peroxiredoxin 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See prdx5 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26657473..26664826)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26620778..26628131)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488819 Neighboring gene estrogen-related receptor alpha Neighboring gene si:dkey-19f23.1 Neighboring gene nuclear RNA export factor 1b Neighboring gene BSCL2 lipid droplet biogenesis associated, seipin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables antioxidant activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thioredoxin peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thioredoxin-dependent peroxiredoxin activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cellular response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within fin regeneration IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in hydrogen peroxide catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisomal matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    peroxiredoxin-5, mitochondrial
    NP_001019577.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024406.1NP_001019577.1  peroxiredoxin-5, mitochondrial

      See identical proteins and their annotated locations for NP_001019577.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095755
      UniProtKB/TrEMBL
      A0A8M1N6S8, Q502C8
      Related
      ENSDARP00000151292.1, ENSDART00000186550.1
      Conserved Domains (1) summary
      cd03013
      Location:5160
      PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      26657473..26664826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)