efcab11 EF-hand calcium binding domain 11 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: efcab11provided by ZNC
Official Full Name: EF-hand calcium binding domain 11provided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-348
See related: Ensembl:ENSDARG00000043740 AllianceGenome:ZFIN:ZDB-GENE-050417-348
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110317
Summary: Predicted to enable calcium ion binding activity. Orthologous to human EFCAB11 (EF-hand calcium binding domain 11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (16423721..16533066)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (16415788..16525133)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables enzyme regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: EF-hand calcium-binding domain-containing protein 11

Names: EF-hand domain-containing protein C14orf143 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017812.1 → NP_001017812.1 EF-hand calcium-binding domain-containing protein 11

See identical proteins and their annotated locations for NP_001017812.1

Status: PROVISIONAL

Source sequence(s)

BC092868

UniProtKB/Swiss-Prot

Q568G4

Related

ENSDARP00000064232.3, ENSDART00000064233.5

Conserved Domains (2) summary

PTZ00183
Location:9 → 156

PTZ00183; centrin; Provisional

cd00051
Location:95 → 152

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...