cisd1 CDGSH iron sulfur domain 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cisd1provided by ZNC
Official Full Name: CDGSH iron sulfur domain 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1162
See related: Ensembl:ENSDARG00000079516 AllianceGenome:ZFIN:ZDB-GENE-040426-1162
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63561; si:dkey-18n13.4
Summary: Predicted to enable 2 iron, 2 sulfur cluster binding activity and L-cysteine transaminase activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within regulation of autophagy. Predicted to be located in intracellular membrane-bounded organelle and membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to human CISD1 (CDGSH iron sulfur domain 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (41910342..41917029, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (41784372..41791059, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IBA Inferred from Biological aspect of Ancestor more info
enables 2 iron, 2 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables L-cysteine transaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in intracellular iron ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of autophagy	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: CDGSH iron-sulfur domain-containing protein 1

NP_956899.1

EC 2.6.1.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.