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    acot17 acyl-CoA thioesterase 17 [ Danio rerio (zebrafish) ]

    Gene ID: 572757, updated on 9-Dec-2024

    Summary

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    Official Symbol
    acot17provided by ZNC
    Official Full Name
    acyl-CoA thioesterase 17provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2381
    See related
    Ensembl:ENSDARG00000088524 AllianceGenome:ZFIN:ZDB-GENE-040426-2381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77651; wu:fc48e10
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in membrane. Is expressed in liver and yolk syncytial layer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See acot17 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (25678113..25690533)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (25688915..25701335)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA thioesterase 14 Neighboring gene peroxisomal succinyl-coenzyme A thioesterase-like Neighboring gene acyl-CoA thioesterase 16 Neighboring gene acyl-CoA thioesterase 18 Neighboring gene laminin, beta 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity. Jima DD, et al. Mol Immunol, 2009 Apr. PMID 19200601, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77651

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acyl-CoA thioesterase 17
    Names
    peroxisomal acyl-CoA thioesterase-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213247.2 → NP_998412.2  acyl-CoA thioesterase 17

      Status: VALIDATED

      Source sequence(s)
      AI877534, BC152651, BX640593, CF348542, EB796040, EH590856
      UniProtKB/TrEMBL
      A0A8N1TRK1, A5PMN5, A7YYG3
      Related
      ENSDARP00000066942.5, ENSDART00000066943.7
      Conserved Domains (2) summary
      pfam04775
      Location:29 → 155
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:219 → 431
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      25678113..25690533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021475137.2 → XP_021330812.1  acyl-CoA thioesterase 17 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PHJ7, A7YYG3, Q5RH34
      Related
      ENSDARP00000091510.4, ENSDART00000100737.5
      Conserved Domains (2) summary
      pfam04775
      Location:2 → 129
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:193 → 405
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394556.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      164456..176868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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