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    slc25a3a solute carrier family 25 member 3a [ Danio rerio (zebrafish) ]

    Gene ID: 393688, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc25a3aprovided by ZNC
    Official Full Name
    solute carrier family 25 member 3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1673
    See related
    Ensembl:ENSDARG00000027424 AllianceGenome:ZFIN:ZDB-GENE-040426-1673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    slc25a3l; zgc:73110
    Summary
    Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to act upstream of or within mitochondrial phosphate ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including alar plate midbrain region; musculature system; optic vesicle; pronephric duct; and visual system. Orthologous to human SLC25A3 (solute carrier family 25 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See slc25a3a in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (16844973..16853474, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (16855996..16864709, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene glycogen synthase 2 Neighboring gene kisspeptin 2 Neighboring gene lactate dehydrogenase Ba Neighboring gene thymopoietin a Neighboring gene serine/threonine kinase receptor associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A novel neuropeptide in suppressing luteinizing hormone release in goldfish, Carassius auratus. Liu Y, et al. Mol Cell Endocrinol, 2013 Jul 15. PMID 23623870
    2. Regulation of spermatogonial development by Fsh: The complementary roles of locally produced Igf and Wnt signaling molecules in adult zebrafish testis. Safian D, et al. Gen Comp Endocrinol, 2019 Dec 1. PMID 31415728
    3. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC73110

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial phosphate ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 25 member 3a
    Names
    solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3, like
    solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328572.1 → NP_001315501.1  solute carrier family 25 member 3a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      BX649476
      UniProtKB/TrEMBL
      A0A8M1PFP1, A0A8M2BBW5, Q6PC47
      Related
      ENSDARP00000140665.1, ENSDART00000164570.2
      Conserved Domains (2) summary
      PTZ00169
      Location:63 → 329
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:53 → 144
      Mito_carr; Mitochondrial carrier protein

    2. NM_200715.2 → NP_957009.1  solute carrier family 25 member 3a

      See identical proteins and their annotated locations for NP_957009.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      BX649476, EH451459, EH478503, EH609753
      UniProtKB/TrEMBL
      A0A8M1PFP1, A0A8M2BBW5, Q6PC47
      Related
      ENSDARP00000111699.2, ENSDART00000125743.4
      Conserved Domains (2) summary
      PTZ00169
      Location:63 → 329
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:53 → 144
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      16844973..16853474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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