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    capza1b capping actin protein of muscle Z-line subunit alpha 1b [ Danio rerio (zebrafish) ]

    Gene ID: 474327, updated on 9-Dec-2024

    Summary

    Official Symbol
    capza1bprovided by ZNC
    Official Full Name
    capping actin protein of muscle Z-line subunit alpha 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031002-24
    See related
    Ensembl:ENSDARG00000056090 AllianceGenome:ZFIN:ZDB-GENE-031002-24
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb852; zK16K6.1; wu:fb36c09; wu:fc85a01; wu:fj45f05; zgc:101755; si:dkey-16k6.1
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Predicted to act upstream of or within actin filament capping. Predicted to be located in cytoplasm. Predicted to be part of F-actin capping protein complex. Predicted to be active in cortical cytoskeleton. Is expressed in adaxial cell; myotome; somite; and trunk. Orthologous to several human genes including CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See capza1b in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (27807974..27817489)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (27788835..27798350)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene Mov10 RNA helicase b, tandem duplicate 1 Neighboring gene wingless-type MMTV integration site family, member 2Bb Neighboring gene CTTNBP2 N-terminal like b Neighboring gene uncharacterized LOC137490329

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within actin filament capping IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in barbed-end actin filament capping IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of F-actin capping protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of F-actin capping protein complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cortical cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    F-actin-capping protein subunit alpha-1b
    Names
    F-actin capping protein alpha-1 subunit
    capping protein (actin filament) muscle Z-line, alpha 1b
    scapping protein (actin filament) muscle Z-line, alpha 1b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006663.1NP_001006664.1  F-actin-capping protein subunit alpha-1b

      See identical proteins and their annotated locations for NP_001006664.1

      Status: VALIDATED

      Source sequence(s)
      AL845328, BC083268, CN841765
      UniProtKB/TrEMBL
      B5DDC0, F6PDN8, Q5XJN1, Q6ZM50
      Related
      ENSDARP00000072971.5, ENSDART00000078509.6
      Conserved Domains (1) summary
      pfam01267
      Location:14282
      F-actin_cap_A; F-actin capping protein alpha subunit

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      27807974..27817489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394727.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      776976..786440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395273.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      1087..6184
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)