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    Chchd4l1 coiled-coil-helix-coiled-coil-helix domain containing 4 like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501576, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Chchd4l1provided by RGD
    Official Full Name
    coiled-coil-helix-coiled-coil-helix domain containing 4 like 1provided by RGD
    Primary source
    RGD:1564534
    See related
    EnsemblRapid:ENSRNOG00000032038 AllianceGenome:RGD:1564534
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564534
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein import into mitochondrial intermembrane space. Predicted to be located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 34.7), Spleen (RPKM 21.6) and 8 other tissues See more
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    Genomic context

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    See Chchd4l1 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (62690390..62696524)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (58696582..58702716)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (63053031..63059164)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene SUPT20H like 2 Neighboring gene suprabasin-like Neighboring gene serine and arginine rich splicing factor 3, pseudogene 2 Neighboring gene Supt20h like 1 Neighboring gene 14-3-3 protein sigma-like Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. RGD1564534 represses NLRP3 inflammasome activity in cerebral injury following ischemia-reperfusion by impairing miR-101a-3p-mediated Dusp1 inhibition. Fan W, et al. Exp Neurol, 2023 Jan. PMID 36336032
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RGD1564534 represses NLRP3 inflammasome activity in cerebral injury following ischemia-reperfusion by impairing miR-101a-3p-mediated Dusp1 inhibition.
      Title: RGD1564534 represses NLRP3 inflammasome activity in cerebral injury following ischemia-reperfusion by impairing miR-101a-3p-mediated Dusp1 inhibition.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-disulfide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-disulfide reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein maturation by protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_028321.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC111405
      Related
      ENSRNOT00000043280.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      62690390..62696524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001048046.1: Suppressed sequence

      Description
      NM_001048046.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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