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    Apmap adipocyte plasma membrane associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366227, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Apmapprovided by RGD
    Official Full Name
    adipocyte plasma membrane associated proteinprovided by RGD
    Primary source
    RGD:1308874
    See related
    EnsemblRapid:ENSRNOG00000006795 AllianceGenome:RGD:1308874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ab2-305; RGD1308874
    Summary
    Predicted to enable arylesterase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cell surface and membrane. Orthologous to human APMAP (adipocyte plasma membrane associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 934.2), Liver (RPKM 460.3) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Apmap in Genome Data Viewer
    Location:
    3q41
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (159869451..159897727, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (139409021..139437296, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (146376828..146407259, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene galactokinase 1 like 1 Neighboring gene ribosomal protein SA, pseudogene 6 Neighboring gene cystatin F Neighboring gene acyl-CoA synthetase short-chain family member 1 Neighboring gene uncharacterized LOC102547396 Neighboring gene visual system homeobox 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Localization and characterization of the novel protein encoded by C20orf3. Ilhan A, et al. Biochem J, 2008 Sep 15. PMID 18513186
    2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC125177

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables arylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables arylesterase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables strictosidine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    adipocyte plasma membrane-associated protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034003.2 → NP_001029175.1  adipocyte plasma membrane-associated protein isoform 3

      See identical proteins and their annotated locations for NP_001029175.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      Q3KR93, Q7TP48
      UniProtKB/TrEMBL
      A0A8L2Q3J0
      Conserved Domains (4) summary
      COG3386
      Location:33 → 280
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cd05819
      Location:62 → 97
      NHL; NHL repeat [structural motif]
      cl18310
      Location:56 → 244
      NHL; NHL repeat unit of beta-propeller proteins
      cl22863
      Location:161 → 248
      Str_synth; Strictosidine synthase

    2. NM_001398965.1 → NP_001385894.1  adipocyte plasma membrane-associated protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8L2Q3J0, A6KHF4
      Related
      ENSRNOP00000008932.8, ENSRNOT00000008931.10
      Conserved Domains (2) summary
      COG3386
      Location:72 → 319
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cl22863
      Location:200 → 287
      Str_synth; Strictosidine synthase

    3. NM_001398966.1 → NP_001385895.1  adipocyte plasma membrane-associated protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Related
      ENSRNOP00000111325.1, ENSRNOT00000138959.1
      Conserved Domains (2) summary
      COG3386
      Location:72 → 284
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cl22863
      Location:200 → 280
      Str_synth; Strictosidine synthase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      159869451..159897727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284289.1 → XP_063140359.1  adipocyte plasma membrane-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A0G2K6G2, A0A8L2Q3J0
      Related
      ENSRNOP00000073800.2, ENSRNOT00000091310.3

    2. XM_063284288.1 → XP_063140358.1  adipocyte plasma membrane-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZUF8, A0A8L2Q3J0
      Related
      ENSRNOP00000082165.1, ENSRNOT00000099680.2

    3. XM_063284290.1 → XP_063140360.1  adipocyte plasma membrane-associated protein isoform X3

      UniProtKB/Swiss-Prot
      Q3KR93, Q7TP48
      UniProtKB/TrEMBL
      A0A8L2Q3J0

    4. XM_006235217.4 → XP_006235279.1  adipocyte plasma membrane-associated protein isoform X4

      UniProtKB/TrEMBL
      A0A8L2Q3J0
      Conserved Domains (2) summary
      COG3386
      Location:1 → 243
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cl22863
      Location:124 → 211
      Str_synth; Strictosidine synthase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TP48.2 GenPept UniProtKB/Swiss-Prot:Q7TP48

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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