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    Chst7 carbohydrate sulfotransferase 7 [ Mus musculus (house mouse) ]

    Gene ID: 60322, updated on 27-Nov-2024

    Summary

    Official Symbol
    Chst7provided by MGI
    Official Full Name
    carbohydrate sulfotransferase 7provided by MGI
    Primary source
    MGI:MGI:1891767
    See related
    Ensembl:ENSMUSG00000037347 AllianceGenome:MGI:1891767
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GST5; C6ST-2; Gn6st-4; glcNAc6ST-4; 2600013M07Rik
    Summary
    Enables chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Is active in Golgi apparatus. Is expressed in several structures, including brain; endocrine gland; immune system; respiratory system; and tail unsegmented mesenchyme. Orthologous to human CHST7 (carbohydrate sulfotransferase 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in lung adult (RPKM 3.9), ovary adult (RPKM 3.0) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Chst7 in Genome Data Viewer
    Location:
    X A1.3; X 15.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (19925202..19965361)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (20058963..20099991)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36, pseudogene 10 Neighboring gene STARR-seq mESC enhancer starr_46872 Neighboring gene STARR-seq mESC enhancer starr_46873 Neighboring gene predicted gene 5384 Neighboring gene STARR-seq mESC enhancer starr_46874 Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 7 Neighboring gene 40S ribosomal protein SA pseudogene Neighboring gene STARR-seq mESC enhancer starr_46875 Neighboring gene STARR-positive B cell enhancer ABC_E11046 Neighboring gene transcription initiation factor IIA subunit 1-like Neighboring gene retinitis pigmentosa 2 homolog

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-acetylglucosamine 6-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables N-acetylglucosamine 6-O-sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables N-acetylglucosamine 6-O-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chondroitin 6-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chondroitin 6-sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables chondroitin 6-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in N-acetylglucosamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in N-acetylglucosamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in N-acetylglucosamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chondroitin sulfate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chondroitin sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 7
    Names
    N-acetylglucosamine 6-O-sulfotransferase 1
    N-acetylglucosamine 6-O-sulfotransferase 4
    carbohydrate (N-acetylglucosamino) sulfotransferase 7
    chondroitin 6-sulfotransferase 2
    galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5
    NP_068361.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021715.1NP_068361.1  carbohydrate sulfotransferase 7 precursor

      See identical proteins and their annotated locations for NP_068361.1

      Status: VALIDATED

      Source sequence(s)
      AB040710
      Consensus CDS
      CCDS30040.1
      UniProtKB/Swiss-Prot
      Q99NB0, Q9EP78
      Related
      ENSMUSP00000043222.8, ENSMUST00000044138.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      19925202..19965361
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_878032.4 RNA Sequence