orc-2 Origin recognition complex subunit 2 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: orc-2
Official Full Name: Origin recognition complex subunit 2
Primary source: WormBase:WBGene00003882
Locus tag: CELE_F59E10.1
See related: AllianceGenome:WB:WBGene00003882
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication. Located in nuclear chromosome. Orthologous to human ORC2 (origin recognition complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See orc-2 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 6

Sequence:: Chromosome: II; NC_003280.10 (10873931..10877683)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F59E10.1 (e-PCR)
- UniSTS:314552

F59E10.3 (e-PCR)
- UniSTS:320996

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA replication origin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nuclear chromosome	IDA Inferred from Direct Assay more info	PubMed
part_of nuclear origin of replication recognition complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of origin recognition complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Origin recognition complex subunit 2

NP_496339.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

10873931..10877683

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063938.6 → NP_496339.1 Origin recognition complex subunit 2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496339.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21037

Conserved Domains (1) summary

pfam04084
Location:138 → 405

ORC2; Origin recognition complex subunit 2