dpm-1 Dolichol-phosphate mannosyltransferase subunit 1 [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: dpm-1
Official Full Name: Dolichol-phosphate mannosyltransferase subunit 1
Primary source: WormBase:WBGene00022044
Locus tag: CELE_Y66H1A.2
See related: AllianceGenome:WB:WBGene00022044
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable dolichyl-phosphate beta-D-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; and protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Orthologous to human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See dpm-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 3

Sequence:: Chromosome: IV; NC_003282.8 (445677..448449)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

Y66H1A.2 (e-PCR)
- UniSTS:320420

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables dolichyl-phosphate beta-D-mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables dolichyl-phosphate beta-D-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in GPI anchor biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dolichol-linked oligosaccharide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein O-linked mannosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: Dolichol-phosphate mannosyltransferase subunit 1

NP_001368307.1

Confirmed by transcript evidence

NP_499931.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

445677..448449

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067530.7 → NP_499931.2 Dolichol-phosphate mannosyltransferase subunit 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499931.2

Status: REVIEWED

UniProtKB/TrEMBL

Q9TYJ7

Conserved Domains (1) summary

PLN02726
Location:1 → 235

PLN02726; dolichyl-phosphate beta-D-mannosyltransferase
NM_001380009.1 → NP_001368307.1 Dolichol-phosphate mannosyltransferase subunit 1 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

U4PF58

Conserved Domains (1) summary

PLN02726
Location:1 → 47

PLN02726; dolichyl-phosphate beta-D-mannosyltransferase