aqp-6 Aquaporin [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: aqp-6
Official Full Name: Aquaporin
Primary source: WormBase:WBGene00000174
Locus tag: CELE_C32C4.2
See related: AllianceGenome:WB:WBGene00000174
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables water channel activity. Involved in water transport. Located in neuronal cell body and non-motile cilium. Is expressed in IL1 neuron. Orthologous to human AQP8 (aquaporin 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See aqp-6 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 7

Sequence:: Chromosome: V; NC_003283.11 (10648446..10651997)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

C32C4.2 (e-PCR)
- UniSTS:313794

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables channel activity	IEA Inferred from Electronic Annotation more info
enables water channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables water channel activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in water transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in non-motile cilium	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Aquaporin

NP_001256245.1

Confirmed by transcript evidence

NP_001256246.1

Confirmed by transcript evidence

NP_001256248.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

10648446..10651997

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001269316.4 → NP_001256245.1 Aquaporin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001256245.1

Status: REVIEWED

UniProtKB/TrEMBL

D5MCS1

Conserved Domains (1) summary

cd00333
Location:58 → 280

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
NM_001269317.4 → NP_001256246.1 Aquaporin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001256246.1

Status: REVIEWED

UniProtKB/TrEMBL

H2FLH4

Conserved Domains (1) summary

cd00333
Location:60 → 282

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
NM_001269319.3 → NP_001256248.1 Aquaporin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001256248.1

Status: REVIEWED

UniProtKB/TrEMBL

Q18352

Conserved Domains (1) summary

cd00333
Location:13 → 235

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...