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    ptr-1 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191746, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ptr-1
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00004216
    Locus tag
    CELE_C24B5.3
    See related
    AllianceGenome:WB:WBGene00004216
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. Orthologous to human PTCHD3 (patched domain containing 3 (gene/pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ptr-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (9177949..9181719, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene putative aldehyde oxidase gad-3 Neighboring gene ncRNA Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Spastin homolog Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene DUF1907 domain-containing protein Neighboring gene Seven TM Receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Limited microsynteny between the genomes of Pristionchus pacificus and Caenorhabditis elegans. Lee KZ, et al. Nucleic Acids Res, 2003 May 15. PMID 12736304, Free PMC Article
    2. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
    3. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
    4. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article
    5. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within nematode male tail mating organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SSD domain-containing protein
    NP_505380.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9177949..9181719 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072979.4 → NP_505380.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505380.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18129
      Conserved Domains (1) summary
      pfam02460
      Location:47 → 926
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

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