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    clec-91 C-type lectin domain-containing protein 91 [ Caenorhabditis elegans ]

    Gene ID: 172736, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-91
    Official Full Name
    C-type lectin domain-containing protein 91
    Primary source
    WormBase:WBGene00014117
    Locus tag
    CELE_ZK858.3
    See related
    AllianceGenome:WB:WBGene00014117
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Is expressed in germ line. Orthologous to human CLEC2L (C-type lectin domain family 2 member L); KLRB1 (killer cell lectin like receptor B1); and KLRG1 (killer cell lectin like receptor G1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-91 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (9126140..9127101, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Poly(A) RNA polymerase gld-4 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene t-SNARE coiled-coil homology domain-containing protein Neighboring gene Protein maternal effect lethal 26;Protein roadkill Neighboring gene TM2 domain-containing protein ZK858.5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Body stiffness is a mechanical property that facilitates contact-mediated mate recognition in Caenorhabditis elegans. Weng JW, et al. Curr Biol, 2023 Sep 11. PMID 37541249, Free PMC Article
    2. Proteomic analysis of Caenorhabditis elegans. Jeong PY, et al. Methods Mol Biol, 2009. PMID 19381582
    3. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein 91
    NP_492448.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9126140..9127101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060047.5 → NP_492448.1  C-type lectin domain-containing protein 91 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492448.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94417
      Conserved Domains (1) summary
      smart00034
      Location:78 → 215
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94417.1

    Gene LinkOut

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