txdc-9 Thioredoxin domain-containing protein 9 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: txdc-9
Official Full Name: Thioredoxin domain-containing protein 9
Primary source: WormBase:WBGene00006515
Locus tag: CELE_C05D11.3
See related: AllianceGenome:WB:WBGene00006515
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in microtubule cytoskeleton organization. Located in cytoplasm and nucleus. Is expressed in nervous system; pharynx; and vulva. Orthologous to human TXNDC9 (thioredoxin domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See txdc-9 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (6432178..6433145)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

expressed throughout development with higher levels of expression in most cells of the nervous system and in vulva; results indicate that C05D11.3 is essential for proper microtubule organization and function
Title: An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C05D11.10 (e-PCR)
- UniSTS:315411

C05D11.3 (e-PCR)
- UniSTS:320453

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Thioredoxin domain-containing protein 9

NP_498410.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6432178..6433145

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066009.5 → NP_498410.1 Thioredoxin domain-containing protein 9 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498410.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q11183

Conserved Domains (1) summary

cd02989
Location:63 → 175

Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...