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    viro-2 WH1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565684, updated on 9-Dec-2024

    Summary

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    Official Symbol
    viro-2
    Official Full Name
    WH1 domain-containing protein
    Primary source
    WormBase:WBGene00015107
    Locus tag
    CELE_B0280.13
    See related
    AllianceGenome:WB:WBGene00015107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be active in cytoplasm. Is expressed in intestinal cell and somatic cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See viro-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (7128901..7132056)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Probable-ribose 5-phosphate isomerase Neighboring gene Uncharacterized protein Neighboring gene Protection of telomeres homolog 1 Neighboring gene putative geranylgeranyl transferase type-2 subunit beta Neighboring gene K Homology domain-containing protein Neighboring gene ncRNA Neighboring gene Putative tyrosine-protein phosphatase B0280.11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Evolutionarily Conserved Pathway Essential for Orsay Virus Infection of Caenorhabditis elegans. Jiang H, et al. mBio, 2017 Sep 5. PMID 28874467, Free PMC Article
    2. The alg-1 Gene Is Necessary for Orsay Virus Replication in Caenorhabditis elegans. Cubillas C, et al. J Virol, 2023 Apr 27. PMID 37017532, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WH1 domain-containing protein
    NP_741212.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7128901..7132056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171181.7 → NP_741212.2  WH1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741212.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5WRU4
      Conserved Domains (1) summary
      cl17171
      Location:23 → 133
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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