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    abhd-3.2 AB hydrolase-1 domain-containing protein;Protein abhd-3.2 [ Caenorhabditis elegans ]

    Gene ID: 180450, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abhd-3.2
    Official Full Name
    AB hydrolase-1 domain-containing protein;Protein abhd-3.2
    Primary source
    WormBase:WBGene00016644
    Locus tag
    CELE_C44C1.5
    See related
    AllianceGenome:WB:WBGene00016644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acetylesterase activity and monoacylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Orthologous to human ABHD1 (abhydrolase domain containing 1) and ABHD3 (abhydrolase domain containing 3, phospholipase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abhd-3.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (975525..978008, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene Vacuolar protein sorting-associated protein 45 Neighboring gene ncRNA Neighboring gene G protein-coupled receptor Neighboring gene Diacylglycerol kinase Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations. Vogt MC, et al. Sci Adv, 2023 Apr 7. PMID 37027477, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acetylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in medium-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in medium-chain fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    AB hydrolase-1 domain-containing protein;Protein abhd-3.2
    NP_001024458.1
    • Confirmed by transcript evidence
    NP_001024459.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      975525..978008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029287.7 → NP_001024458.1  Protein abhd-3.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024458.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18610
      Conserved Domains (2) summary
      pfam00561
      Location:108 → 351
      Abhydrolase_1; alpha/beta hydrolase fold
      cl21494
      Location:56 → 366
      Abhydrolase; alpha/beta hydrolases

    2. NM_001029288.5 → NP_001024459.1  AB hydrolase-1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024459.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G8JY22
      Conserved Domains (1) summary
      cl21494
      Location:56 → 249
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18610.1

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