cope-1 Coatomer subunit epsilon [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cope-1
Official Full Name: Coatomer subunit epsilon
Primary source: WormBase:WBGene00009732
Locus tag: CELE_F45G2.4
See related: AllianceGenome:WB:WBGene00009732
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Located in mitochondrion. Orthologous to human COPE (COPI coat complex subunit epsilon). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cope-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (13426264..13427721)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F45G2.4 (e-PCR)
- UniSTS:306320

F45G2.3 (e-PCR)
- UniSTS:307656

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of COPI vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
located_in COPI-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed

General protein information

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Preferred Names: Coatomer subunit epsilon

NP_499771.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

13426264..13427721

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067370.7 → NP_499771.1 Coatomer subunit epsilon [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499771.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O62246

Conserved Domains (2) summary

pfam04733
Location:3 → 291

Coatomer_E; Coatomer epsilon subunit

sd00004
Location:172 → 197

PPR; PPR repeat [structural motif]