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    dpy-1 VWFA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175342, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpy-1
    Official Full Name
    VWFA domain-containing protein
    Primary source
    WormBase:WBGene00001063
    Locus tag
    CELE_M01E10.2
    See related
    AllianceGenome:WB:WBGene00001063
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in body morphogenesis and regulation of growth. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dpy-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    20
    Sequence:
    Chromosome: III; NC_003281.10 (2034988..2048007, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene ATS3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of larval growth in C. elegans cuticle mutants. Nyaanga J, et al. MicroPubl Biol, 2022. PMID 36411799, Free PMC Article
    2. Isolation and mapping of DNA probes within the linkage group I gene cluster of Caenorhabditis elegans. Starr T, et al. Genome, 1989 Jun. PMID 2744447
    3. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Leung-Hagesteijn C, et al. Cell, 1992 Oct 16. PMID 1384987
    4. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Ewald CY, et al. Nature, 2015 Mar 5. PMID 25517099, Free PMC Article
    5. The genetic and RFLP characterization of the left end of linkage group III in Caenorhabditis elegans. Pilgrim D. Genome, 1993 Aug. PMID 8104844

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in body morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    VWFA domain-containing protein
    NP_001367968.1
    • Confirmed by transcript evidence
    NP_001370799.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2034988..2048007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001384037.2 → NP_001370799.1  VWFA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SNP7
      Conserved Domains (2) summary
      pfam00092
      Location:823 → 975
      VWA; von Willebrand factor type A domain
      cl27758
      Location:1050 → 1299
      Zona_pellucida; Zona pellucida-like domain

    2. NM_001381759.2 → NP_001367968.1  VWFA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TXR6
      Conserved Domains (2) summary
      smart00241
      Location:717 → 966
      ZP; Zona pellucida (ZP) domain
      pfam00092
      Location:490 → 642
      VWA; von Willebrand factor type A domain
    Nucleotide Protein
    Heading Accession and Version

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